Hodgkins lymphoma and non hodgkins lymphoma survival rates. Although they are very similar in many ways, the treatment for them is not quite the same. With the help of additional immunohistochemistry it is possible to distinguish chl from tcell. Learn vocabulary, terms, and more with flashcards, games, and other study tools. What is difference between hodgkins and non hodgkins lymphoma. There are many differences between the two conditions while some presenting features, investigations and general treatment principles are the same for both hodgkin and non hodgkin lymphomas. The distinction between hodgkin s disease and non hodgkin s lymphoma is made upon examination of the cancer cells from a biopsy or aspiration of the tumor tissue. If youve been diagnosed with hodgkin lymphoma or are worried about it, you likely have a lot of questions. Nonhodgkin lymphoma is the seventh most common cause of cancerrelated deaths in the united states. Both adult hodgkin lymphoma and nonhodgkin lymphoma are types of cancer that develop in the lymphatic system, part of the bodys immune system the difference between hodgkin lymphoma and nonhodgkin lymphoma is that the cancer develops in different lymphocytes.
These large, malignant cells are found in diseased tissues and are thought to be a type of malignant b lymphocyte. Hodgkin lymphoma, also known as hodgkins disease, is a type of lymphoma, a cancer of the lymphatic system. Brief summaries of two commonly encountered types of nonhodgkin lymphomadiffuse histiocytic lymphoma and nodular, lymphocytic, poorly differentiated lymphoma rappaport et al 1 classificationillustrate some of the variability of features and natural. Mar 10, 2016 lymphomas are the most common form of cancer in teens ages 15 to 19. Cure leukemia, lymphoma, hodgkins disease and myeloma, and improve the quality of life of patients and their families. Get an overview of hodgkin lymphoma and the latest key statistics in the us. The majority of non hodgkin patients are over the age of 55 when first diagnosed, whereas the median age for diagnosis of hodgkin lymphoma is 39. Hodgkin lymphoma has a particular appearance under the microscope and contains cells called reedsternberg cells. What is the exact difference between hodgkins lymphoma. Treatment may consist of chemotherapy, radiation therapy, bone marrow or stem cell transplantation or a combination of these treatments. Medical professionals are able to distinguish non hodgkins from hodgkins lymphoma formerly referred to as hodgkins disease by examining the white blood cells affected by the disease. Hodgkin vs non hodgkin lymphoma hodgkin and non hodgkin are two important subtypes of lymphocyte cancers. Hodgkin vs nonhodgkin lymphoma hodgkin and nonhodgkin are two important subtypes of lymphocyte cancers. What is the difference between hodgkins disease and non.
Whats the difference between hodgkin and nonhodgkin. Beyond that, malignant lymphomas differ in their etiology, pathogenesis, genetics, clinical manifestations, patterns of spread, response to treatment, and survival. Apr 21, 2018 lymphoma explained clearly hodgkin s vs non hodgkin s pathology remastered duration. From the archival tissues of hodgkins original cases available today. The risk of developing non hodgkin lymphoma increases with age and it is more common in males. Hodgkin lymphoma most often occurs in people ages 15 to 24 and in people over 60.
Treatments for the two diseases can vary, so its important that your doctor make an accurate diagnosis. Nhl is treated with different chemotherapy than hd. Knowing the difference between hodgkins vs nonhodgkins lymphoma will provide a strong understanding of this blood cancer. The type of abnormal cells identified in the sample determines whether a lymphoma is classified as. A doctor can tell the difference between hodgkin s lymphoma and non hodgkin s lymphoma by examining the cancer cells under a microscope. Whats the difference between hodgkin and nonhodgkin lymphoma. The primary difference between hodgkin s disease and non hodgkin s lymphoma is the presence of a specific abnormal cell. Are hodgkins lymphoma and nonhodgkins lymphoma the same. Pdf relationship between classical hodgkins lymphoma and. Apr 16, 20 what is the difference between hodgkin s and non hodgkin s lymphoma. If a specific type of abnormal cell called a reedsternberg cell is detected, the lymphoma is classified as hodgkin s. Difference between hodgkins and non hodgkins lymphoma. Hodgkins lymphoma vs nonhodgkins lymphoma difference.
Symptoms and signs include swollen lymph nodes, fever, night sweats, coughing, weakness, chest pain, unexplained weight loss, and abdominal pain. A family friend was recently diagnosed with nonhodgkins lymphoma. Apr 11, 2015 most lymphomas are nonhodgkin lymphoma. Kimmer is 35 year old female, presenting neck lymphadenopathy few weeks postpartum. While both types of cancer develop in the same way, the single factor that distinguishes the two is a single type of cell the reed sternberg cell. Nonhodgkin lymphoma is the most common hematologic malignancy, with an estimated 70, cases diagnosed in the united states in 2012. Key statistics for nonhodgkin lymphoma nonhodgkin lymphoma nhl is one of the most common cancers in the united states, accounting for about 4% of all cancers. Mohrbacher, md, associate professor of clinical medicine at the keck school of medicine of usc, answers questions about leukemia, lymphoma and non malignant blood disorders. Difference between hodgkin and nonhodgkin lymphoma compare. The median age of patients with nonhodgkin lymphoma is 60, but it occurs in all age groups. Hodgkins and nonhodgkins lymphomas health and medical. A biopsy of the enlarged lymph node or other tissue is an essential first step. The type of abnormal cells identified in the sample determines whether a lymphoma is classified as hodgkin s disease or nonhodgkin s lymphoma.
What is the difference between hodgkins and nonhodgkins lymphoma. Pdf on sep 1, 2011, richard t hoppe and others published hodgkin lymphoma find, read and cite all the research you need on researchgate. Nonhodgkin lymphoma is more common than hodgkin lymphoma. Whats the difference between hodgkin versus nonhodgkin.
Good prognosis lymphocytes, vrs cells, the cure rate is about 93%. The primary difference between hodgkins disease and nonhodgkins lymphoma is the presence of a specific abnormal cell. Nonhodgkin lymphoma represents a wide spectrum of illnesses that vary from the most indolent to the most aggressive malignancies. There are more than 60 distinct types of nonhodgkin lymphoma, whereas hodgkin lymphoma is a more homogeneous disease. The distinction between hodgkins disease and nonhodgkins lymphoma is made upon examination of the cancer cells from a biopsy or aspiration of the tumor tissue. The distinction between hodgkin s disease and nonhodgkin s lymphoma is made upon examination of the cancer cells from a biopsy or aspiration of the tumor tissue. They are called hodgkin lymphoma hl and non hodgkin lymphoma nhl. Nonhodgkin lymphoma an overview sciencedirect topics. Reedsternberg cells named after the doctors that first described them in detail. Both hodgkins lymphoma and nonhodgkins lymphoma are lymphomas a type of cancer that begins in a subset of white blood cells called lymphocytes. Lymphoma explained clearly hodgkins vs non hodgkins pathology remastered duration. Besides, patients with hodgkin lymphoma tend to be younger. Nonhodgkins lymphoma is cancer of the lymphatic system, a vital part of the bodys immune system. Lymphocytes are an important part of your immune system.
Hodgkins disease was the first form of lymphoma described and defined in 1832. What s the difference between hodgkin s lymphoma and non hodgkin s lymphoma. Hodgkins lymphoma is identified by the presence of reedsternberg cells. The term nonhodgkin lymphomas is applied to a group of diverse neoplasms that arise in the reticuloendothelial system. Key difference lymphoma vs non hodgkins lymphoma the malignancies of the lymphoid system are called the lymphomas. But there are important differences between the two. Hodgkin lymphoma, also known as hodgkin s disease, is a type of lymphoma, a cancer of the lymphatic system. Both hodgkin lymphoma formerly known as hodgkin s disease and non hodgkin lymphoma also known as non hodgkin s lymphoma are lymphomas, a type of cancer that originates in a subset of white blood cells called lymphocytes. Relationship between classical hodgkins lymphoma and diffuse large bcell lymphoma. Hodgkins lymphoma vs nonhodgkins lymphoma difference and. Many different grades of nhl low grade, intermediate, high while hd is not divided into grades.
If the doctor does not detect what is known as a reedsternberg cell, the lymphoma is classified as non hodgkins. For nhl, the overall five and 10 year relative survival rates are 69 percent and 59 percent, respectively. Medcram medical lectures explained clearly 9,477 views 16. Hodgkins disease nonhodgkins lymphoma multiple myeloma. The lymphatic system is a network of nodes knots of tissue connected by vessels that. B cells and t cells play different roles in the bodys immune response to disease. The main difference between these two diseases lies in the lymphocyte each involves. The difference between the two was originally historical, but today hl and nhl are also known to differ in their microscopic appearances, typical course, and other characteristics. It is important for doctors to be able to tell the difference between hodgkins and non hodgkins lymphomas as they are two different diseases. Nonhodgkin lymphoma is also a malignancy of lymphocytes and can be derived from b cells or t cells. It is important to get started and take some action as. Mar 11, 2014 hodgkin vs non hodgkin lymphoma hodgkin and non hodgkin are two important subtypes of lymphocyte cancers. Pdf on jan 1, 2011, salvia jain and others published relationship between classical. The american cancer society s estimates for non hodgkins lymphoma in 2020 are.
Nonhodgkins lymphoma nhl is a group of lymphomas affecting lymphoid tissue. The difference between the two was originally historical, but today hl and nhl are also known to differ in their microscopic appearances, typical course, and other. A lymphoma is widely found among children of developing nations. In addition to the presence or lack of reedsternberg cells, other differences between hodgkin and nonhodgkin lymphoma include that.
Hodgkins and nonhodgkin lymphoma are types of blood cancer that originate in lymphocytes, or white blood cells. Nonhodgkins lymphoma, on the other hand, is a very diverse set of cancers basically any lymphoma that is not hodgkins disease gets classified as nonhodgkins lymphoma. Her prospects of joining the academic ranks in pathology at johns. Click to read about diagnosis, symptoms and treatment. Thomas hodgkin, the groundbreaking researcher who chronicled symptoms of the diseases.
For hodgkins lymphoma, the survival rates are usually improved as the five year survival rate is 85 percent and a 10 year survival rate of 80. These cells malignant mature b cells and are especially large. Hd usually occurs in the young adult and the elderly. Rituxumab has revolutionized how non hodgkins lymphoma is treated. Hodgkins disease is considered one of the most treatable forms of cancer if found early. Every patients prognosis is different, but hodgkins disease, for the most part, can be treated and managed. While both types of cancers develop in your immune system, the difference in the lymphomas is the type of cell the lymphoma is developed from. Perhaps this singular distinction has been achieved through the continued use of the eponymous hodgkin for two types of lymphomas. Hodgkins lymphoma, or hl, and non hodgkins lymphoma, or nhl, are the two main categories of lymphoma. They are called hodgkin lymphoma hl and nonhodgkin lymphoma nhl. On the contrast, non hodgkins lymphoma involves b cells or t cells.
The risk of developing nonhodgkin lymphoma increases with. Some common kinds of nonhodgkins lymphoma include burkitts, diffuse large bcell, mantle cell, and follicular. Difference between lymphoma and non hodgkins lymphoma. Hodgkin lymphoma was named after the doctor who first recognised it. Treatment for nhl depends on disease stage, the patients general health and other factors. Answers from trusted physicians on hodgkins vs nonhodgkins. Mohrbacher, md, associate professor of clinical medicine at the keck school of medicine of usc, answers questions about leukemia, lymphoma and. According to the national institutions of health of the united states, about 5% of cancer of lymphoma and less than 1% of cancer of hodgkins lymphoma is found within all types of cancer in the united states. Multiple myeloma is still not curable, but survival has increased greatly due to new therapies. What are the treatment options for nonhodgkins lymphoma. Your doctor can tell the type of lymphoma you have by using a microscope to look for reed. Hodgkins lymphoma and nonhodgkins lymphoma are not the same disease, although they are both cancers of the lymphatic system.
About 77,240 people 42,380 males and 34,860 females will be diagnosed with nhl. Just to add, my late dad had non hodgkins lymphoma back in the 80s, when he was around 52y old but he was diagnosed early when he discovered his lump at his groin enlarged inguinal lymph node. Lymphoma is a cancer involving lymphocytes, a type of white blood cell. Lymphoma information hodgkin lymphoma nonhodgkin lymphoma.
If a specific type of abnormal cell called a reedsternberg cell is detected, the lymphoma is classified as hodgkins. Hodgkin s lymphoma and non hodgkin s lymphoma are not the same disease, although they are both cancers of the lymphatic system. A doctor can tell the difference between hodgkins lymphoma and nonhodgkins lymphoma by examining the cancer cells under a microscope. If in examining the cells, the doctor detects the presence of a specific type of abnormal cell called a reedsternberg cell, the lymphoma is classified as hodgkin s. Hodgkin s lymphoma is identified by the presence of reedsternberg cells. If in examining the cells, the doctor detects the presence of a specific type of abnormal cell called a reedsternberg cell, the lymphoma is classified as hodgkins. The common factor is the malignant cell, a lymphocyte.
Lls funds lifesaving blood cancer research around the world, provides free information and support services, and is the voice for all blood cancer patients seeking access to quality, affordable, coordinated care. Both adult hodgkin lymphoma and nonhodgkin lymphoma are types of cancer that develop in the lymphatic system, part of the bodys immune system. Hodgkins and non hodgkins lymphoma aprof graham young senior staff specialist institute of haematology royal prince alfred hospital sydney slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Treatments for the two diseases can vary, so it s important that your doctor make an accurate diagnosis. Mar 08, 2009 non hodgkin s lymphoma, on the other hand, is a very diverse set of cancers basically any lymphoma that is not hodgkin s disease gets classified as non hodgkin s lymphoma. These large, malignant cells are found in diseased tissues and are thought to be a. Both hodgkin lymphoma formerly known as hodgkins disease and nonhodgkin lymphoma also known as nonhodgkins lymphoma are lymphomas, a type of cancer that originates in a subset of white blood cells called lymphocytes. What is the difference between hodgkins lymphoma and non.
Hodgkins disease is highly curable, but has risks of secondary cancers. Oct 30, 20 explore stephentranthams board hodgkins and non hodgkins lymphoma. Some common kinds of non hodgkin s lymphoma include burkitt s, diffuse large bcell, mantle cell, and follicular. Clinical non hodgkins lymphoma nhl tends to involve lymph nodes ln in the periphery like epitroclear elbow and waldeyers ring tonsils and adenoids, this is unusual in hodgkins lymphoma. Jan 21, 2009 hodgkins and non hodgkins lymphoma aprof graham young senior staff specialist institute of haematology royal prince alfred hospital sydney slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The first is called non hodgkin s lymphoma, and the other is known as hodgkin s lymphoma, and both arise from lymphocytes, a type of white blood cell. What is the exact difference between hodgkins lymphoma and. Combining the monoclonal antibody rituximab rituxan with chemotherapy. The first is called nonhodgkins lymphoma, and the other is known as hodgkins lymphoma, and both arise from lymphocytes, a type of white blood cell. There are many differences between the two conditions while some presenting features, investigations and general treatment principles are the same for both hodgkin and nonhodgkin lymphomas.
Polymerase chain reaction pcr for jk gene joining region gene of kappa light chain. About nonhodgkin lymphoma what is nonhodgkin lymphoma. Nonhodgkin lymphoma, by contrast, can be derived from b cells or t cells and can arise in the lymph nodes as well as other organs. In any person suspected of having a lymphoma, it is crucial to distinguish between hodgkins disease and nhl and to determine which type of hodgkins or nhl is present, since the course of the disease and the treatment differs a great deal. The type of abnormal cells identified in the sample determines whether a lymphoma is classified as hodgkin s disease or non hodgkin s lymphoma. What is the difference between hodgkins disease and lymphoma. There are more than 60 distinct types of non hodgkin lymphoma, whereas hodgkin lymphoma is a more homogeneous disease. What is difference between hodgkins and non hodgkins. Difference between hodgkin and nonhodgkin lymphoma.
Understanding hodgkin lymphoma hodgkins disease basic. I know about hodgkins lymphoma, but i dont know very much about nonhodgkins. Nhl is the seventh most common malignancy in the united states with a. They are a fairly common variety of cancers whose incidence has rapidly grown during the past few decades, principally due to the increase in the number of immunocompromised hosts. What are the differences between hodgkins and nonhodgkins. Whats the difference between hodgkins lymphoma and nonhodgkins lymphoma. The difference between hodgkin lymphoma and nonhodgkin lymphoma is that the cancer develops in different lymphocytes. Patients suffering from both hodgkins disease and nonhodgkins lymphoma. Moffitt explains the differences between hodgkin and nonhodgkin lymphoma in this helpful article. Non hodgkin lymphoma is the seventh most common cause of cancerrelated deaths in the united states.
Non hodgkin s lymphoma is cancer of the lymphatic system, a vital part of the body s immune system. Nonhodgkin lymphoma also known as nonhodgkins lymphoma, nhl, or sometimes. They are traditionally divided into hodgkins lymphoma which. Jul 06, 2015 the median age of patients with non hodgkin lymphoma is 60, but it occurs in all age groups. If you or someone close have recently been diagnosed, you may be overwhelmed by emotions ranging from anger to disbelief to fear. The cause of hodgkins lymphoma is abnormal reedsternberg cells. This site is for those seeking information on lymphoma.
Hodgkins vs nonhodgkins lymphoma flashcards quizlet. A family friend was recently diagnosed with non hodgkin s lymphoma. Non hodgkin s lymphoma nhl encompasses a heterogeneous group of neoplasms of the lymphoid system. I know about hodgkin s lymphoma, but i dont know very much about non hodgkin s. Cure leukemia, lymphoma, hodgkin s disease and myeloma, and improve the quality of life of patients and their families. What is the difference in treatment for hodgkins and non. What is the difference between hodgkins and nonhodgkins. It usually affects young adults and has a 5year survival rate of about 84%.